OK, I'll take a stab at it to start you off.
I believe your Skywatcher HEQ5 is a german equatorial mount (GEM). That is, you point it roughly at the north star when you set up (or at southern pole in the southern hemisphere). This process is called polar alignment and you need to learn to do that if you haven't already. For mounts like that, if you were to start tracking an object on the Eastern half of the sky, eventually it will cross the Meridian (though it's possible it will do that after dawn). In the northern hemisphere, the Meridian is the imaginary line running from the North Star heading towards the Southern Pole going through the Zenith, the high-point in the sky overhead. When your object crosses the Meridian, the front of your telescope will be pointing mostly up, and the back end where your camera is would be pointing mostly down (you have a refractor, so the camera is on the back end). After the object crosses the Meridian, your telescope, still tracking the object would start pointing at lower altitudes. The problem is, the back-end/camera would start going underneath your mount, into your tripod, and the camera will probably will hit something down there, causing the motion to stall, and potentially breaking or mis-aligning your mount, and certainly ruining your imaging session. To get around that, instead of continuing to track the object smoothly after the object crosses the Meridian, (usually after a little delay) the telescope switches to the other side of the mount (the back of your telescope would move to the east side, the front toward the west side), and as it tracks, now the bottom will be moving away from the tripod, instead of towards it. That switching of sides is called a Meridian Flip.
Jasem has posted a few videos on how to set up Ekos to do a Meridian Flip, e.g.
and there's plenty of discussion of it in the forum
and on YouTube and CloudyNights and elsewhere.
My 2 cents would be to simply check the box in the Mount tab which says "Flip if HA > ___" and fill in the value with something like 0.20 hours.
Start your imaging session. Use KStars or stellarium or other planitarium software to see if and when your object will be crossing the Meridian.
If it wil, don't trust the automated flip the first time, or until you've been successful with a few times. That is, instead be there watching/supervising it,
and be prepared to stop things if it looks like it going to crash, and/or if doesn't do the flip at all (and will eventually crash into the tripod).
When the session is running, while your object is East of the Meridian, the Indi Control Panel's mount tab, main control should indicate
"West (pointing East)", and after the flip it should say "East (Pointing West)". The Ekos mount tab should tell you how many hours and minutes
it is before the meridian flip will occur. If your mount is "West (Pointing East)" according to the Indi Control Panel, the mount tab it should NOT say Meridian Flip disabled.
You can also verify by eye that the telescope/mount is correctly labeled as "West (Pointing East)" or "East (Pointing West)".
Before you start, make sure your cables won't catch on anything, loosen the clutches and make sure the mount is able to move around freely then tighten them,
set up, and see if you can get the flip to succeed. It took me a while to get it to work reliably, but now I'd say it works pretty well.
This was all "off the cuff", please watch the videos to learn more, but you should be able to accomplish this.